Lower urinary tract symptoms in children with anorectal malformations with rectoperineal fistulas

Pernilla Stenström1, Hanna Sandelin2, Ragnhild Emblem3

  • 1Department of Pediatric Surgery, Skane University Hospital, Institution of Clinical Science, Lund University.

Insights

Children with anorectal malformations with rectoperineal fistulas (ARM-P) experience more lower urinary tract symptoms (LUTS) than healthy peers. Those with urinary tract anomalies (UTA) show increased LUTS, necessitating regular follow-up.

Area of Science:

  • Pediatric Surgery
  • Urology
  • Congenital Malformations

Background:

  • Anorectal malformations with rectoperineal fistulas (ARM-P) are congenital conditions that can impact multiple organ systems.
  • Lower urinary tract symptoms (LUTS) are common in children but their prevalence in those with ARM-P requires further investigation.

Purpose of the Study:

  • To determine the frequency of LUTS in children diagnosed with ARM-P.
  • To compare LUTS prevalence in children with ARM-P against a control group, analyzing gender-specific differences.
  • To assess the impact of concomitant urinary tract anomalies (UTA) on LUTS in the ARM-P cohort.

Main Methods:

  • Utilized the International Children's Continence Society 2014 definitions for LUTS.
  • Collected data from children aged 4-12 years undergoing surgery for ARM-P across two international pediatric surgery centers.
  • Compared LUTS, urinary tract infections, and medication use between the ARM-P patient group and a control cohort, stratified by gender and presence of UTA.

Main Results:

  • Children with ARM-P exhibited a higher incidence of LUTS compared to controls.
  • The frequency of urinary tract infections and daily urinary medication use was significantly greater in the ARM-P group.
  • Patients with co-occurring UTA reported more frequent urinary infections than those without UTA.

Conclusions:

  • Children with ARM-P demonstrate a higher burden of LUTS than their healthy counterparts.
  • The presence of concomitant UTA exacerbates LUTS in children with ARM-P.
  • Routine screening for both UTA and LUTS is recommended for children diagnosed with ARM-P.
Abstract

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