Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Micturition Reflex01:26

The Micturition Reflex

3.5K
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
3.5K
Urinary Bladder01:23

Urinary Bladder

4.2K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
4.2K
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

2.5K
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
2.5K
Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

2.1K
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
2.1K
Neural Regulation01:37

Neural Regulation

44.7K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
44.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Impact of Obesity on Perioperative Complications in Prolapse Patients ≥ 70 Years Old.

International urogynecology journal·2026
Same author

Outcomes following intradetrusor onabotulinumtoxinA injections and sacral neuromodulation in older men.

BJUI compass·2026
Same author

Determining a Real-world Definition of Percutaneous Tibial Nerve Stimulation Induction Therapy in Medicare Beneficiaries With Overactive Bladder.

Urology·2026
Same author

Reply to Editorial Comment on "Clinician- and Geographic-level Variation in Utilization of Sacral Neuromodulation and OnabotulinumtoxinA Injections Among Medicare Beneficiaries With Overactive Bladder".

Urology·2025
Same author

Utilization of More Than One Minimally Invasive Overactive Bladder Therapy Among Older Adults; a National Medicare Study.

Neurourology and urodynamics·2025
Same author

Clinician- and Geographic-level Variation in Utilization of Sacral Neuromodulation and OnabotulinumtoxinA Injections Among Medicare Beneficiaries With Overactive Bladder.

Urology·2025

Related Experiment Video

Updated: Mar 25, 2026

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
10:26

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

Published on: August 18, 2014

27.0K

Neuromodulation in neurogenic bladder.

Melissa T Sanford1, Anne M Suskind1

  • 1Department of Urology, University of California, San Francisco, CA, USA.

Translational Andrology and Urology
|February 24, 2016
PubMed
Summary
This summary is machine-generated.

Neuromodulation, including sacral and percutaneous tibial nerve stimulation (PTNS), shows promise for neurogenic lower urinary tract dysfunction. This review explores outcomes and considerations for this patient group.

Keywords:
Neurogenic bladderimplantable neurostimulators

More Related Videos

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
06:36

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

7.8K
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

2.4K

Related Experiment Videos

Last Updated: Mar 25, 2026

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology
10:26

Bladder Smooth Muscle Strip Contractility as a Method to Evaluate Lower Urinary Tract Pharmacology

Published on: August 18, 2014

27.0K
A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
06:36

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling

Published on: November 28, 2019

7.8K
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

2.4K

Area of Science:

  • Urology
  • Neurology
  • Medical Devices

Background:

  • Neuromodulation is established for non-neurogenic bladder conditions.
  • Its use in neurogenic bladder dysfunction is emerging.
  • This necessitates a review of specific applications.

Purpose of the Study:

  • To examine the outcomes of neuromodulation in neurogenic bladder.
  • To identify contraindications for these treatments.
  • To discuss special considerations for sacral and PTNS in this population.

Main Methods:

  • Review of current literature on neuromodulation for neurogenic bladder.
  • Analysis of outcomes data for sacral nerve stimulation and PTNS.
  • Identification of contraindications and special considerations.

Main Results:

  • Neuromodulation offers potential treatment benefits for neurogenic bladder.
  • Specific outcomes vary based on stimulation type and patient factors.
  • Contraindications and patient selection are critical for success.

Conclusions:

  • Sacral and PTNS are viable options for neurogenic lower urinary tract dysfunction.
  • Careful patient selection and management are essential.
  • Further research will refine neuromodulation's role in this field.