Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Base Excision Repair01:54

Base Excision Repair

27.7K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
27.7K
Base Excision Repair01:54

Base Excision Repair

5.5K
5.5K
Mesh Analysis01:20

Mesh Analysis

1.7K
Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
1.7K
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

8.3K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
8.3K
Mesh Analysis with Current Sources01:10

Mesh Analysis with Current Sources

2.2K
Mesh analysis becomes simpler when analyzing circuits with current sources, whether independent or dependent. The presence of current sources reduces the number of equations required for analysis. Two cases illustrate this:
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association Between Clean-Catch and Catheterized Urine Samples in Obese Females.

Urogynecology (Philadelphia, Pa.)·2026
Same author

Patient Perceptions of Pessaries for Treatment of Pelvic Organ Prolapse.

Urogynecology (Philadelphia, Pa.)·2025
Same author

Study design and outcomes measures: The influence of composite endpoints and other design variables on outcomes in a study of a novel device for stress urinary incontinence.

Neurourology and urodynamics·2018
Same author

Editorial Comment.

Neurourology and urodynamics·2016
Same author

Surgical repair of pelvic organ prolapse in elderly patients.

Current opinion in urology·2016
Same author

Outcomes of Midurethral Slings in Women with Concomitant Preoperative Severe Lower Urinary Tract Voiding Symptoms.

Ochsner journal·2015
Same journal

Single Port Robotic Surgery in Benign Urologic Disease - A Review of Contemporary Applications and Outcomes.

Current urology reports·2026
Same journal

Effective Mentorship in Urology Fellowship Training: Qualities, Models, and Equity.

Current urology reports·2026
Same journal

Management of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis.

Current urology reports·2026
Same journal

Lower Urinary Tract Symptoms as an Indicator of Occult Neurologic Disease: A System-first Framework for Urologic Practice.

Current urology reports·2026
Same journal

Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.

Current urology reports·2026
Same journal

Is Open Partial Nephrectomy Still an Option in the Robotic Era?

Current urology reports·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.5K

Mesh Excision: Is Total Mesh Excision Necessary?

Gillian F Wolff1, J Christian Winters1, Ryan M Krlin2

  • 1Department of Urology, Louisiana State University Health Sciences Center, 1542 Tulane Avenue, New Orleans, LA, 70112, USA.

Current Urology Reports
|February 25, 2016
PubMed
Summary
This summary is machine-generated.

Pelvic organ prolapse (POP) repair with polypropylene mesh (PPM) may require repeat surgery. While mesh complications occur, total removal is not always necessary unless obstruction or erosion is present.

Keywords:
CystoceleExposurePerforationRectoceleSling obstructionVaginal vault prolapse

More Related Videos

A Finite Element Approach for Locating the Center of Resistance of Maxillary Teeth
10:50

A Finite Element Approach for Locating the Center of Resistance of Maxillary Teeth

Published on: April 8, 2020

10.3K
3D Printing of Preclinical X-ray Computed Tomographic Data Sets
11:06

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

41.1K

Related Experiment Videos

Last Updated: Mar 25, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.5K
A Finite Element Approach for Locating the Center of Resistance of Maxillary Teeth
10:50

A Finite Element Approach for Locating the Center of Resistance of Maxillary Teeth

Published on: April 8, 2020

10.3K
3D Printing of Preclinical X-ray Computed Tomographic Data Sets
11:06

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

41.1K

Area of Science:

  • Urology
  • Gynecology
  • Surgical Innovation

Background:

  • Pelvic organ prolapse (POP) recurrence necessitates repeat surgery in nearly 29% of women.
  • Transvaginal repairs increasingly use polypropylene mesh (PPM) to augment prolapse repair.
  • Concerns regarding PPM safety have emerged due to mesh-specific complications.

Purpose of the Study:

  • To review complications associated with transvaginal mesh placement.
  • To evaluate the necessity of total versus partial mesh removal for complication resolution.
  • To inform clinical decision-making regarding mesh removal strategies.

Main Methods:

  • Literature review of studies on transvaginal mesh for POP repair.
  • Analysis of complications, including exposures, erosion, dyspareunia, and pelvic pain.
  • Examination of evidence supporting total versus partial mesh removal.

Main Results:

  • Substantive evidence for intrinsic PPM properties necessitating total removal is lacking without complications.
  • Surgical intervention is warranted for certain mesh complications after conservative therapy failure.
  • High-quality studies do not consistently show total mesh removal superior for pain reduction.

Conclusions:

  • Mesh removal is indicated for obstruction and erosion, often resolving symptoms.
  • Patients must be informed of potential complications associated with mesh removal.
  • The decision for total versus partial mesh removal should be individualized based on complications.