Related Experiment Video
Updated: Mar 25, 2026
06:48
Limbal Approach-Subretinal Injection of Viral Vectors for Gene Therapy in Mice Retinal Pigment Epithelium
Published on: August 7, 2015
22.3K
[Epstein-Barr virus associated acute retinal necrosis].
D Roquelaure1, S Harbarth2, J S Schutz1
1Department of Ophthalmology, University Hospitals and School of Medicine, 22 Rue Alcide-Jentzer, Geneva, 1205, Switzerland.
Summary
Epstein-Barr virus (EBV) can cause acute retinal necrosis, a rare condition leading to vision loss. Diagnosing EBV in ocular inflammation cases may help distinguish its role in patient morbidity.
Area of Science:
- Ophthalmology
- Virology
- Infectious Diseases
Background:
- Epstein-Barr virus (EBV) is a known cause of various human diseases.
- Ocular inflammation can have diverse etiologies, some of which are rare.
Observation:
- A 72-year-old male presented with progressive vision loss.
- Clinical suspicion for acute retinal necrosis was raised.
- Vitreous biopsy confirmed the presence of the EBV genome.
Findings:
- The case demonstrates Epstein-Barr virus (EBV) as a causative agent of acute retinal necrosis.
- EBV was the sole pathogen identified in the vitreous biopsy.
Implications:
- EBV screening, though not standard, could aid in diagnosing rare causes of ocular inflammation.
- Identifying EBV's role may improve differentiation between direct causation and coincidental findings in retinal diseases.
