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Updated: Mar 25, 2026

Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
Published on: November 21, 2023
Using goal-driven deep learning models to understand sensory cortex
Daniel L K Yamins1,2, James J DiCarlo1,2
1Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Abstract:
Fueled by innovation in the computer vision and artificial intelligence communities, recent developments in computational neuroscience have used goal-driven hierarchical convolutional neural networks (HCNNs) to make strides in modeling neural single-unit and population responses in higher visual cortical areas. In this Perspective, we review the recent progress in a broader modeling context and describe some of the key technical innovations that have supported it. We then outline how the goal-driven HCNN approach can be used to delve even more deeply into understanding the development and organization of sensory cortical processing.
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