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Updated: Mar 25, 2026
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
Primary Cardiac Osteosarcoma
Ji-Gang Wang1, Bing Liu2, Han Gao3
1Department of Pathology, The Affiliated Hospital of Qingdao University, People's Republic of China; Department of Pathology, School of Basic Medical Sciences, Fudan University, People's Republic of China.
Background:
Primary cardiac osteosarcoma is extremely rare. There is no cohort study on such tumours to date. The aim of this study is to investigate the clinical characteristics and outcome patterns of such tumours.
Methods:
A thorough literature review was performed, and all relevant clinical items were collected. A total of 53 cases of primary cardiac osteosarcoma were enrolled in this study, including 25 males and 28 females.
Results:
The age at diagnosis ranged from 14 to 77 years with a mean age of 43.6 years. The clinical manifestations, imaging features, and laboratory tests of the primary cardiac osteosarcomas were similar to other types of primary cardiac tumours. Sex, tumour size and adjunctive chemo-radiotherapy were found to affect the overall survival pattern.
Conclusions:
The present study may provide an effective consultation for the diagnosis and treatment of this tumour.
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