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Do Not Forget the Glycophorin A: An Unusual Case of Myeloid Sarcoma
Reena D Mohanlal1, Jenifer Vaughan, Narisha Ramparsad
1Departments of *Anatomical Pathology ∥Molecular Medicine and Hematology #Pediatrics, Division of Pediatric Oncology †National Health Laboratory Services ‡Chris Hani Baragwanath Academic Hospital §Faculty of Health Sciences, University of the Witwatersrand ¶Charlotte Maxeke Academic Hospital, Soweto, Johannesburg, South Africa.
Abstract:
Acute erythroid leukemia is rare, with isolated reports on presentation as an extramedullary tumor mass (myeloid sarcoma). We describe a case of pure erythroid leukemia presenting as an orbital mass in a 1-year, 9-month-old girl. This is only the second case described in a child. Tissue biopsy of the tumor mass showed medium-sized cells that were glycophorin A positive and negative with conventional myeloid markers. Flow cytometry, bone marrow aspirate, and trephine confirmed the diagnosis of pure erythroid leukemia.
