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Performance indicators in a newly established organized cervical screening programme: registry-based analysis in the
Ondřej Májek1, Jaroslava Dušková, Vladimír Dvořák
1aInstitute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University bCentre of Outpatient Gynaecology and Primary Care, Brno cInstitute of Health Information and Statistics dInstitute of Pathology, 1st Faculty of Medicine, Charles University eCGOP, Prague, Czech Republic fFinnish Cancer Registry, Helsinki, Finland.
The Czech National Cervical Cancer Screening Programme (CNCCSP) has successfully reduced cervical cancer incidence and mortality since 2008. While screening coverage has improved, quality variations among centers require attention for continued progress.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- The Czech National Cervical Cancer Screening Programme (CNCCSP) was established in 2008, transitioning from opportunistic screening to an organized national program.
- Cervical cancer screening is a critical public health intervention for early detection and prevention.
Purpose of the Study:
- To analyze recent trends in cervical cancer burden in the Czech Republic.
- To evaluate the quality and performance of the CNCCSP using standard indicators.
- To identify variations in screening quality across different centers.
Main Methods:
- Utilized data from the national Cervical Cancer Screening Registry and the Czech National Cancer Registry.
- Calculated internationally accepted performance indicators for cervical cancer screening.
- Assessed temporal trends and geographical variability in screening outcomes.
Main Results:
- Cervical cancer incidence decreased by 21% and mortality by 35% between 1995 and 2011.
- Annual screening coverage increased significantly, reaching 56% in 2013 (77% over a 2-year interval).
- High-grade lesions or malignancy detected in approximately 0.2% of screened women, with a positive predictive value of 79.6% for advanced neoplasia.
Conclusions:
- The CNCCSP demonstrates promising results in reducing cervical cancer burden.
- Continued quality improvement and addressing heterogeneity among screening centers are crucial for sustained success.
- Further research through linkage studies can enhance understanding of screening effectiveness and validity.

