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Published on: April 18, 2011
Fractures Among Inpatients in a Pediatric Hospital
Lisa Swartz Topor1, Joshua S Borus2, Sarah Aspinwall3
1Divisions of Pediatric Endocrinology and Warren Alpert School of Medicine of Brown University, Providence, Rhode Island; lisa_swartz_topor@brown.edu.
Insights
Hospitalized infants, particularly those under one year old and born preterm, are most at risk for fractures. Identifying these fractures requires more than just voluntary reporting systems.
Area of Science:
- Pediatric Bone Health
- Hospital-Acquired Conditions
- Patient Safety
Background:
- Inpatient pediatric fractures are an underrecognized source of harm.
- Limited data exist on the clinical profiles of children experiencing fractures during hospitalization.
- Fractures can impact both current and future bone health in children.
Purpose of the Study:
- To describe the clinical characteristics of pediatric patients who sustained fractures while hospitalized.
- To analyze the incidence and common sites of inpatient pediatric fractures.
- To evaluate the effectiveness of different methods for identifying inpatient fractures.
Main Methods:
- Retrospective identification of inpatient fractures using a voluntary safety event reporting system and electronic medical record keyword searches.
- Collection of clinical characteristics, laboratory data, and survival status from medical records.
- Analysis of fracture locations and patient demographics.
Main Results:
- Fifty-six subjects experienced 128 fractures, most commonly femur and humerus fractures.
- High-risk patient characteristics included age ≤1 year (64%), preterm birth (53%), ICU admission (90%), and immobilization (88%).
- A voluntary reporting system identified only 57% of fractures, highlighting detection limitations.
Conclusions:
- Critically ill, immobilized infants under one year, often born preterm, represent the majority of hospitalized patients with fractures.
- Voluntary reporting systems are insufficient for comprehensive identification of inpatient pediatric fractures.
- Further research is needed on fracture screening strategies and the link between fracture severity, illness, and mortality in hospitalized children.
Objective:
Fractures occurring in hospitalized children may be an underrecognized preventable harm with implications for current and future bone health, but few data exist regarding the clinical characteristics of these pediatric patients. We describe the clinical characteristics of patients who sustained fractures during hospitalization over a 4.5-year period at a single tertiary care center.
Methods:
We retrospectively identified subjects who experienced inpatient fractures using a voluntary safety event reporting system and computer-assisted keyword search of the electronic medical record. We used the medical record to collect clinical characteristics, laboratory data, and survival status.
Results:
The safety event reporting system and keyword search identified 57% and 43% of subjects, respectively. Fifty-six subjects sustained 128 fractures while hospitalized, most frequently at the femur (33 fractures) and humerus (30 fractures). Twenty-seven subjects sustained multiple fractures. Common clinical characteristics included age ≤1 year (64%); preterm birth (53%); admission to an ICU (90%); immobilization (88%); and weight-for-age z score less than or equal to -2.0 (52%). Sixteen (29%) subjects died, and the mortality rate varied by primary diagnosis.
Conclusions:
Critically ill, immobilized infants under 1 year of age and who were often born preterm sustained the majority of fractures occurring during hospitalization. A voluntary reporting system was insufficient to identify all inpatient fractures. Future studies should explore optimal fracture screening strategies and the relationship among fractures, severity of illness and mortality in hospitalized children.
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