Related Experiment Video
Updated: Mar 25, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
Comparison of Clinical Risk Factors Among Pediatric Patients With Single Admission, Multiple Admissions (Without Any
Jeffrey C Winer1, Elena Aragona2, Alan I Fields3
1Wolfson Children's Hospital, Jacksonville, Florida jeffrey.winer@jax.ufl.edu.
Insights
This study on hospital readmissions found that patients with multiple admissions are a high-risk group, regardless of 7-day readmissions. Medical complexity, not care failure, may drive many readmissions.
Area of Science:
- Pediatric healthcare research
- Hospital readmission analysis
- Clinical informatics
Background:
- Hospital readmissions are a growing concern in healthcare.
- Understanding factors influencing hospital utilization is crucial.
- Identifying drivers of 7-day readmissions is a key objective.
Purpose of the Study:
- To identify demographic and clinical factors linked to hospital utilization.
- To determine factors associated with 7-day readmissions in pediatric patients.
- To analyze patient groups based on admission frequency and readmission status.
Main Methods:
- Retrospective case-control study at a children's hospital.
- Categorization of patients into single admission, multiple admissions without 7-day readmission, and multiple admissions with 7-day readmission groups.
- Statistical analysis to identify factors associated with hospital utilization and readmissions.
Main Results:
- Patients with single admissions had fewer medications, less home health care, and fewer diagnoses than those with multiple admissions.
- No significant differences were found between multiple-admission patients with and without 7-day readmissions.
- Multiple admissions appear to represent a single high-risk patient cohort.
Conclusions:
- Multiple admissions characterize a consistent high-risk group, irrespective of 7-day readmission status.
- Medical complexity, rather than care failure, may explain a significant portion of readmissions.
- Further research is needed to evaluate targeted interventions for high-risk patients to reduce hospital utilization.
Background And Objective:
Readmissions have received increasing attention. The goal of this study was to identify demographic and clinical factors associated with hospital utilization and 7-day readmissions.
Methods:
This retrospective case-control study of inpatient and observation encounters was conducted at a freestanding children's hospital. Over a 1-year period, patients were categorized into 3 groups: patients with a single admission, patients with multiple admissions without any 7-day readmissions, and patients with at least one 7-day readmission. Factors associated with risk of future hospital utilization were determined, and post hoc testing was performed to compare groups.
Results:
Patients with a single admission had statistically significant lower numbers of medications at admission and discharge, lower rates of home health care at admission and discharge, and fewer diagnosis codes during index admission than patients with multiple admissions. There were no statistically significant differences among patients with multiple admissions between those with and without 7-day readmissions.
Conclusions:
This study found that patients with multiple admissions were similar regardless of whether they had any 7-day readmissions. Because patients with multiple admissions seemed to represent a single high-risk group, it is possible that many readmissions represent a consequence of medical complexity rather than a failure of care. Further studies are necessary to determine if providing targeted interventions to high-risk patients will lower their future hospital utilization.
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Drug Toxicity: Risk factors
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Methods of Documentation VI: Case Management Model
For example, a patient with a chronic...
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption