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Related Concept Videos

Rational Dosage Regimen: Maintenance Dose and Loading Dose01:24

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A rational dosage regimen considers a drug's pharmacokinetics, including its absorption, distribution, metabolism, and elimination from the body. By understanding these factors, the appropriate dosage can be determined, and the dosing schedule can be designed to achieve and maintain the desired therapeutic effect while minimizing adverse effects.
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
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Dosage Regimens: Designs and Approaches01:28

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Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Determination of Multiple Dosing Parameters: Loading and Maintenance Doses01:25

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A loading dose is an essential pharmacological strategy to rapidly achieve the target plasma drug concentration necessary for an immediate therapeutic effect. This approach is especially critical for drugs characterized by slow absorption or extended half-lives, where delaying therapeutic plasma levels could compromise treatment outcomes. By administering a loading dose, clinicians ensure a prompt onset of drug action, even for agents with complex pharmacokinetic profiles.Achieving steady-state...
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Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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Dosage Regimen: Fixed Dose01:01

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Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
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Dose Size and Dosing Frequency: Determination Methods01:21

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Determining the optimal dose size and dosing frequency in pharmacotherapy is crucial for achieving therapeutic effectiveness while minimizing adverse effects. This article explores the methodologies employed in determining these parameters, focusing on their significance and interplay to tailor dosing regimens.Dose Size: Dose size refers to the amount of a drug administered in a single dose. It is determined based on the drug's pharmacodynamics and pharmacokinetics properties and...
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Updated: Mar 25, 2026

Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals
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Patient Dose Management: Focus on Practical Actions.

Michael Yong Park1, Seung Eun Jung1

  • 1Department of Radiology, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea .

Journal of Korean Medical Science
|February 25, 2016
PubMed
Summary
This summary is machine-generated.

Minimizing medical radiation exposure is crucial. This review details radiation dose reporting, practical optimization strategies, and educational needs for healthcare professionals and the public to ensure safe medical imaging practices.

Keywords:
JustificationMedical ExposureOptimizationRadiation ProtectionRadiation, Ionizing

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Area of Science:

  • Radiology and Medical Physics
  • Public Health and Radiation Safety

Background:

  • Medical radiation is integral to modern diagnostics and therapeutics.
  • Effective radiation use requires justification and optimization to minimize patient exposure.
  • Understanding radiation doses is the first step toward dose reduction.

Purpose of the Study:

  • To review current practices in medical radiation dose reporting across various imaging modalities.
  • To provide practical strategies for optimizing radiation exposure in clinical settings.
  • To highlight the importance of education on radiation safety for medical personnel and the public.

Main Methods:

  • Comprehensive review of radiation units and dose reporting standards in medical imaging.
  • Analysis of current legislation and guidelines concerning radiation dose management.
  • Compilation of practical tips for dose optimization in clinical practice.
  • Assessment of existing educational programs for radiation safety and development of suggested strategies.
  • Inclusion of frequently asked questions and answers regarding radiation dose for patient communication.
  • Discussion of computerized tools for patient dose management.

Main Results:

  • Current medical imaging modalities report radiation dose variably.
  • Legislation and dose reporting standards are evolving to ensure patient safety.
  • Effective dose management requires a combination of technical tools, optimized protocols, and robust education.
  • Patient dose monitoring is essential for optimization but not for individual cancer risk assessment.

Conclusions:

  • Optimizing medical radiation exposure is paramount and achievable through informed practices.
  • Standardized dose reporting, practical optimization techniques, and comprehensive education are key to radiation safety.
  • Medical facilities should implement patient dose management programs, emphasizing justified examinations and avoiding unnecessary procedures.