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Related Experiment Videos

Energy expenditure in early infancy.

P S Davies1, G Ewing, A Lucas

  • 1MRC Dunn Nutrition Unit, Cambridge.

The British Journal of Nutrition
|November 1, 1989
PubMed
Summary

This study measured total energy expenditure in infants using the doubly-labeled water technique. Findings provide new data on infant energy needs and metabolism, crucial for clinical and scientific research.

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Area of Science:

  • Pediatric Nutrition
  • Human Metabolism
  • Biomedical Research

Background:

  • Measuring infant energy expenditure is vital but challenging.
  • Previous methods had ethical and practical limitations.
  • The doubly-labeled water technique is now validated for infants.

Purpose of the Study:

  • To non-invasively measure total energy expenditure in healthy infants.
  • To establish centiles for energy expenditure in early infancy.
  • To inform re-evaluation of infant energy requirements and study metabolic diseases.

Main Methods:

  • Utilized the doubly-labeled water technique.
  • Measured 41 normal, full-term infants.
  • Data collected at approximately 1.5, 3, and 6 months of age.

Main Results:

  • Mean total energy expenditure was 270, 280, and 330 kJ/kg/day at 1.5, 3, and 6 months, respectively.
  • Presented centiles for total energy expenditure in early infancy.
  • Suggested expressing data as kJ/sqrt(kg body-weight/day) is most appropriate.

Conclusions:

  • Established non-invasive measurements of total energy expenditure in infancy.
  • Provides essential data for understanding infant energy requirements.
  • Supports further research into infant metabolic disorders.

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