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Double pathology, sarcoidosis associated with multiple myeloma: A case report
Robert Dachs1, Anria Horn1, Hannes Koornhof2
1Department of Orthopaedic Surgery, University of Cape Town, Cape Town, South Africa.
Journal of Bone Oncology
|February 25, 2016
Summary
This case report highlights the rare co-occurrence of sarcoidosis and multiple myeloma. Awareness of this association is crucial for accurate diagnosis, as skeletal lesions can mimic each other.
Area of Science:
- Oncology
- Immunology
- Rheumatology
Background:
- The co-occurrence of sarcoidosis and multiple myeloma is infrequently documented.
- Distinguishing skeletal manifestations of these conditions presents diagnostic challenges.
Observation:
- A patient with a history of sarcoidosis presented with multiple skeletal lesions identified via MRI.
- Histological examination confirmed the presence of both sarcoidosis (non-necrotising granulomas) and multiple myeloma (plasma cell neoplasm).
Findings:
- This case adds to the limited literature on the dual diagnosis of sarcoidosis and multiple myeloma.
- Radiological and clinical similarities between skeletal lesions of both diseases can lead to diagnostic delays.
Implications:
- Clinicians must consider the possibility of multiple myeloma in sarcoidosis patients presenting with bone lesions.
- Early recognition of this dual pathology is essential for timely and appropriate treatment of multiple myeloma.
