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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
High energy expenditure is not protective against increased adiposity in children
S R J Zinkel1,2, R I Berkowitz3, A J Stunkard3
1University of Wisconsin-Madison Department of Nutritional Sciences.
Insights
Low total energy expenditure (TEE) in early childhood does not predict excess weight at age 8. This study found no link between early-life TEE and later obesity risk in children, regardless of maternal obesity status.
Area of Science:
- Pediatric Endocrinology
- Obesity Research
- Child Development
Background:
- Low total energy expenditure (TEE) is a potential contributor to childhood excess weight.
- Longitudinal data on TEE and its predictive value for obesity are limited.
Purpose of the Study:
- To determine if low TEE in the first six years of life predicts excess weight status at age eight.
- To investigate the relationship between early-life TEE and later obesity development in children at varying risk levels.
Main Methods:
- Measured TEE using doubly labeled water in children from 0.25 to 6 years.
- Assessed weight, stature, waist circumference, fat mass, and fat-free mass (FFM).
- Utilized a linear mixed effects model to analyze TEE, accounting for individual variation and calculating residual TEE.
Main Results:
- Fat-free mass (FFM) strongly correlated with TEE (R² = 0.91); waist circumference and sex were also significant TEE predictors.
- Residual TEE demonstrated individual tracking over time.
- Residual TEE did not correlate with BMI or body fat percentage at age 8.
Conclusions:
- The residual TEE approach did not identify early-life TEE levels that predict excess weight at age 8.
- Early-life TEE, as measured by this method, does not appear to be a significant predictor of obesity in this cohort.
- Findings suggest other factors beyond early TEE influence obesity development in children at high and low risk.
Background:
Low levels of energy expenditure (TEE) may contribute to excess weight during childhood, but limited longitudinal data exist.
Objectives:
This is to test whether low TEE during the first 6 years of life could predict excess weight status at 8 years.
Methods:
Total energy expenditure from doubly labelled water, weight, stature, waist circumference and fat mass and fat-free mass (FFM) in children at 0.25, 2, 4 and 6 years of age. This cohort includes individuals at high (n = 27) and low risk (n = 26) for childhood obesity, based upon whether pre-pregnant maternal obesity. A linear mixed effects model was fit to TEE. Individual variation was accounted for as a random effect. Residual TEE was calculated for age and individually averaged across time.
Results:
Fat-free mass (kg) was highly correlated (R2 = 0.91) with TEE (kcal/day), and waist circumference and sex were also significant predictors of TEE. TEE residual tracked within individuals. TEE residuals did not correlate with either BMI or %fat at age 8 years.
Conclusion:
Using the residual TEE approach to identify high and low TEE during the first 6 years of life did not explain excess weight at 8 years of life in this cohort of children at high and low risk of obesity based upon maternal obesity status.
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