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Direct visualization of an IgM directed against a membrane antigen involved in both cell-matrix interactions and
H Lesot1, J M Meyer, A Staubli
1Institut de Biologie Médicale, CNRS LP 6520, Faculté de Médecine 11, Strasbourg, France.
Biology of the Cell
|January 1, 1989
Abstract:
Dental mesenchymal cells were cultured in the presence of a monoclonal antibody. MC16A16, consisting of IgM and directed against a hydrophobic 165 kDa protein. Since the epitope recognized by MC16A16 was found to be at the outer cell surface, a direct visualization of IgM antibodies was used to localize the 165 kDa antigen by transmission electron microscopy. The present results demonstrate that the 165 kDa antigen is a membrane protein.