Dental Implants in Patients Receiving Chemotherapy: A Meta-Analysis
Related Experiment Video
Updated: Mar 25, 2026
In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
Published on: June 6, 2025
Bruno Ramos Chrcanovic1, Tomas Albrektsson, Ann Wennerberg
1*PhD Student, Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden. †Retired Professor and Former Head of the Department of Biomaterials, Göteborg University, Göteborg, Sweden; Guest Professor of the Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden. ‡Professor and Head of the Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.
Purpose:
To test the null hypothesis of no difference in the implant failure rates, postoperative infection, and marginal bone loss for patients being rehabilitated by dental implants and being versus not being submitted to chemotherapy, against the alternative hypothesis of a difference.
Methods:
An electronic search without time or language restrictions was undertaken in May 2014 in PubMed/MEDLINE, Web of Science, Cochrane Oral Health Group Trials Register plus hand-searching. Eligibility criteria included clinical human studies, either randomized or not.
Results:
Nine publications were included. The results suggested that the insertion of dental implants in patients submitted or not submitted to chemotherapy did not affect the implant failure rates (risk ratio 1.02, 95% confidence interval 0.56-1.85; P = 0.95). Because of lack of enough information, meta-analyses for the outcomes "postoperative infection" and "marginal bone loss" were not performed.
Conclusion:
These results cannot suggest that the insertion of dental implants in patients submitted to chemotherapy may or may not affect the implant failure rates, because of a limited number of published studies, most of them characterized by a low level of specificity and dealing with a limited number of cases without a control group. The reliability and validity of the data collected and the potential for biases and confounding factors are some of the shortcomings of the present study.
More Related Videos
05:54Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
Published on: October 18, 2021
09:10Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures
Published on: August 5, 2021