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Metal-containing and related polymers for biomedical applications
Yi Yan1, Jiuyang Zhang, Lixia Ren
1Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208, USA. tang4@mailbox.sc.edu yanyi@nwpu.edu.cn.
Chemical Society Reviews
|February 25, 2016
Summary
Metal-containing polymers leverage unique properties for biomedical uses, including drug delivery, therapeutics, biosensing, and bioimaging. This review highlights recent advancements in this rapidly growing field.
Area of Science:
- Polymer Chemistry
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- Metal-containing polymers integrate diverse metal elements (e.g., transition metals) into polymer frameworks.
- These materials exhibit unique optical, electrochemical, and magnetic properties.
- Advancements in polymer chemistry and metal-containing drugs have spurred progress in this area.
Purpose of the Study:
- To provide a comprehensive survey of recent progress in the biomedical applications of metal-containing polymers.
- To categorize and discuss key applications based on their function.
- To highlight the potential of these materials in various healthcare domains.
Main Methods:
- Literature review focusing on recent advancements in metal-containing polymers for biomedical applications.
- Categorization of applications into drug delivery, polymeric drugs/biocides, biosensors, and bioimaging.
- Analysis of how metal incorporation influences polymer properties and biological interactions.
Main Results:
- Metal-containing polymers are utilized as effective drug delivery vehicles.
- They function as polymeric drugs and biocides, including antimicrobial, antiviral, anticancer, photodynamic, and radiotherapy agents.
- Applications extend to biosensing and advanced bioimaging.
Conclusions:
- Metal-containing polymers represent a versatile platform for diverse biomedical applications.
- Their unique properties enable innovative solutions in drug development, diagnostics, and imaging.
- Continued research promises further expansion of their therapeutic and diagnostic potential.
