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Current needs in pediatric pharmacoepidemiology

Tamar Lasky1, Al Artaman2, Angela S Czaja3

  • 1MIE Resources, Baltimore, MD, USA.

Pharmacoepidemiology and Drug Safety
|February 25, 2016
PubMed

Insights

A needs assessment by the International Society of Pharmacoepidemiology (ISPE) Pediatric Special Interest Group (SIG) identified critical needs in pediatric pharmacoepidemiology. Key challenges include limited sample sizes and missing data crucial for child-specific research.

Area of Science:

  • Pharmacoepidemiology
  • Pediatric Research
  • Public Health

Background:

  • Pediatric pharmacoepidemiology is an emerging sub-specialty.
  • The International Society of Pharmacoepidemiology (ISPE) Pediatric Special Interest Group (SIG) identified a need for a comprehensive assessment.

Purpose of the Study:

  • To identify critical needs and future directions in pediatric pharmacoepidemiology.
  • To understand current activities and methodologic challenges in the field.

Main Methods:

  • A mixed-methods survey using structured interviews was conducted.
  • Interviews involved SIG members and the wider ISPE membership over 2013-2014.
  • SIG members conducted and summarized the interviews.

Main Results:

  • Twenty-nine ISPE members participated, reporting work with 59 distinct databases.
  • Limited sample sizes were a significant issue for 57% of respondents, especially for subgroups.
  • Missing data elements included detailed medication info, parental links, and age-specific data like birthweight and developmental status.

Conclusions:

  • The needs assessment provides a preliminary overview of pediatric pharmacoepidemiology.
  • Methodologic challenges unique to pediatric pharmacoepidemiologic research were documented.
Abstract

Keywords:
childrenneeds assessmentpediatricspharmacoepidemiology

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