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Venous thromboembolism - prevalence and risk factors in chronic venous disease patients

Dalibor Musil1, Markéta Kaletová1, Jiří Herman2

  • 11 Department of Internal Medicine I - Cardiology, Teaching Hospital, Olomouc, Czech Republic.

Phlebology
|February 26, 2016
PubMed

Insights

The prevalence of venous thromboembolism (VTE) in chronic venous disease patients is 5%. Advanced age (≥70 years) and obesity significantly increase VTE risk in these patients.

Area of Science:

  • Vascular Medicine
  • Epidemiology

Background:

  • Chronic venous disease (CVD) affects a significant portion of the population.
  • Venous thromboembolism (VTE) is a serious complication that can occur in patients with CVD.
  • Understanding the prevalence and risk factors for VTE in CVD patients is crucial for effective management.

Purpose of the Study:

  • To investigate the prevalence of venous thromboembolism (VTE) in patients diagnosed with chronic venous disease (CVD).
  • To identify intrinsic and extrinsic risk factors associated with the occurrence of VTE in this patient cohort.

Main Methods:

  • A retrospective study was conducted on 641 outpatients with primary chronic venous disease (CVD).
  • Data collected included patient demographics, body mass index (BMI), family history of VTE, CEAP clinical classification, smoking status, and hormone therapy use.
  • The prevalence of VTE was analyzed in relation to these potential risk factors.

Main Results:

  • The overall prevalence of VTE episodes was 5% among patients with CVD, with no significant gender predominance.
  • Age ≥70 years (OR 3.2-4.78) and obesity (p=0.002) were strongly associated with an increased risk of VTE.
  • Chronic venous insufficiency showed a higher prevalence of VTE (55.3%) compared to varicose veins (44.7%).
  • Family history of VTE, smoking, and hormone therapy were not found to be significant independent risk factors for VTE.

Conclusions:

  • The 5% VTE prevalence in CVD patients is comparable to the general European population.
  • Age ≥70 years and obesity are significant risk factors for VTE in patients with chronic venous disease.
  • Obese patients with CVD face a higher VTE risk than obese individuals in the general population, highlighting the need for targeted prevention strategies.

Keywords:
BMIChronic venous diseaseagegenderprevalencevenous thromboembolism

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