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CIRCLE-Seq for Interrogation of Off-Target Gene Editing

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Lessons Learned from Native C.I.R.C.L.E., a Culturally Specific Resource.

Andrea Garcia¹, Lisa Baethke², Judith S Kaur^3,4

¹Division of Chronic Disease and Injury Prevention, Los Angeles County Department of Public Health, 3530 Wilshire Blvd, 8th Floor, Los Angeles, CA, 90010, USA.

Journal of Cancer Education : the Official Journal of the American Association for Cancer Education

|February 26, 2016

Summary

This summary is machine-generated.

The American Indian/Alaska Native Cancer Information Resource Center and Learning Exchange (Native C.I.R.C.L.E.) has significantly increased culturally relevant cancer information dissemination. This initiative aims to bridge the digital divide for American Indian/Alaska Native populations.

Keywords:

American Indian/Alaska Native Aommunity education Digital divide

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Area of Science:

Public Health
Health Disparities
Health Communication

Background:

Cancer is the second leading cause of death for American Indians and Alaska Natives (AIAN).
Cancer mortality trends show poorer outcomes in AIAN compared to non-Hispanic Whites.
Culturally appropriate health information is crucial for addressing AIAN cancer disparities.

Purpose of the Study:

To analyze trends in the distribution and access of culturally relevant cancer information materials.
To compare access to printed versus online cancer information resources.
To evaluate the impact of the American Indian/Alaska Native Cancer Information Resource Center and Learning Exchange (Native C.I.R.C.L.E.) over 15 years.

Main Methods:

Analysis of data accumulated by Native C.I.R.C.L.E. since its inception in 2000.
Tracking the distribution of print materials globally.
Monitoring the number of print material requests and online downloads.

Main Results:

The availability of culturally appropriate cancer materials has increased more than 10-fold.
Print materials are distributed worldwide.
Thousands of print and online materials are accessed monthly.

Conclusions:

Native C.I.R.C.L.E. has successfully expanded the reach of culturally relevant cancer information.
Efforts are underway to address the digital divide by targeting the AIAN public more directly.
Continued dissemination of accessible cancer information is vital for improving AIAN health outcomes.