Related Experiment Video
Updated: Mar 25, 2026

Functional Isolation of Single Motor Units of Rat Medial Gastrocnemius Muscle
Published on: December 26, 2020
Analysis of motor unit firing characteristics in patients with motor neuron diseases
Pınar Yalinay Dikmen1, Elif Kocasoy Orhan2, M Barış Baslo2
1a Department of Neurology, Acibadem University School of Medicine , Istanbul , Turkey ;
Abstract:
This study was designed to evaluate firing rate variability in patients with upper/lower motor neuron disorders. Twenty healthy subjects and 19 patients with motor neuron disorders participated in the study. Consecutive motor unit action potential pairs from extensor digitorum communis (EDC) muscle were recorded from each subject with trigger-delay line mode. Patients with motor neuron disorders (17.7 ± 10.8 ms) showed significantly higher mean time variability of interpotential interval value than healthy volunteers (10.3 ± 0.1 ms) (p < 0.001).
More Related Videos
06:08Author Spotlight: Studying Neuromuscular Responses and Motor Neuron Plasticity in Neurodegenerative Diseases
Published on: April 19, 2024
09:07Electrophysiological Motor Unit Number Estimation MUNE Measuring Compound Muscle Action Potential CMAP in Mouse Hindlimb Muscles
Published on: September 25, 2015
Related Concept Videos
Motor Units
Motor units come in different sizes, with smaller units...
Motor Units
Motor Unit Stimulation
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Neuromuscular Junction And Blockade