Related Experiment Video
Updated: Mar 25, 2026
Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
Reduced iron parameters and cognitive processes in children and adolescents with DM1 compared to those with standard
Ewa Mojs1, Maia Stanisławska-Kubiak1, Rafał W Wójciak1
1Department of Clinical Psychology, Poznan University of Medical Sciences, Poznań, wielkopolskie, Poland.
Insights
Children with type 1 diabetes and reduced iron levels may experience impaired cognitive function. Early screening for iron deficiency is crucial in these young patients to prevent potential cognitive deficits.
Area of Science:
- Pediatrics
- Endocrinology
- Neuroscience
Background:
- Anemia is common in diabetic patients and can worsen disease complications.
- Iron deficiency in children with type 1 diabetes is linked to cognitive impairment.
Purpose of the Study:
- To investigate the relationship between reduced iron parameters and cognitive performance in children and adolescents with type 1 diabetes.
Main Methods:
- Assessed 100 children (6-17 years) with type 1 diabetes.
- Measured blood parameters (RBC, hemoglobin, iron levels) and cognitive function using the Wechsler Intelligence Scale for Children (WISC-R).
Main Results:
- Children with type 1 diabetes and lower iron concentrations showed significantly reduced non-verbal intelligence scores on the WISC-R.
Conclusions:
- Reduced iron parameters in children with type 1 diabetes correlate with impaired cognitive function.
- Routine screening for iron deficiency and preventive measures are recommended for all children with type 1 diabetes.
Abstract:
Anemia in patients with diabetes is not scarce and may contribute to the complications of the disease. The risk of iron deficiency parameters in child sufferers of diabetes type 1, observed in studies, can lead to cognitive impairment. The aim of the study was to determine whether children and adolescents with diabetes type 1, in whom reduced ferric parameters are observed in control tests, may also show reduced cognitive performance. The study included 100 children with diabetes type 1 at the age of 6-17 years. During control tests, patients' morphological blood parameters were measured: red blood cells (RBC), hemoglobin, glycosylated hemoglobin, hematocrit, RBC volume, the molar mass of hemoglobin in RBC (MCH), mean corpuscular hemoglobin in RBC and iron concentrations in serum using flame atomic absorption spectroscopy and the Wechsler Intelligence Scale for Children (WISC-R). Results in the group of children with a diabetes type 1 significantly lower concentration of three ferric parameters affect the non-verbal intelligence measured with WISC-R. The prevalence of reduced ferric parameters justifies further screening in all children with diabetes type 1 and taking up appropriate preventive measures to reduce the risk of their occurrence.
More Related Videos
07:32Assessing Iron Deposition in the Brains of 5xFAD Mice by Perls'/DAB Staining
Published on: May 23, 2025
09:40Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
Published on: January 19, 2017