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Related Concept Videos

Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Transplant I: Introduction01:28

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Chronic Kidney Disease II: Clinical Manifestations01:24

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Updated: Mar 25, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Bone Disease after Kidney Transplantation.

Antoine Bouquegneau1, Syrazah Salam2, Pierre Delanaye1

  • 1Department of Nephrology, Dialysis, and Transplantation, Centre Hospitalier Universitaire de Liege, Liege, Belgium.

Clinical Journal of the American Society of Nephrology : CJASN
|February 26, 2016
PubMed
Summary

Kidney transplant recipients frequently experience bone and mineral disorders, increasing fracture and mortality risks. This review details recent advances in understanding and managing these complex post-transplant conditions.

Keywords:
Bone DiseasesMetabolicOsteoporosisVitamin Dfibroblast growth factor 23fractureglucocorticoidskidney transplantationmineral metabolismparathyroid hormonerenal osteodystrophy

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Area of Science:

  • Nephrology
  • Endocrinology
  • Bone Metabolism

Background:

  • Bone and mineral disorders are common in kidney transplant recipients.
  • These disorders increase risks of fracture, morbidity, and mortality.
  • Conditions include osteoporosis and high/low-turnover bone disease.

Purpose of the Study:

  • To review recent advancements in understanding mineral and bone disorders (MBDs) in kidney transplant recipients.
  • To highlight improvements in diagnostics and therapeutics for post-transplant MBDs.

Main Methods:

  • Review of recent scientific literature and data.
  • Focus on prevalence, pathophysiology, and management strategies.

Main Results:

  • Pathophysiology involves interplay of pre-existing renal osteodystrophy, immunosuppression, and altered mineral metabolism (PTH-VitD-FGF23 axis).
  • Current noninvasive diagnostic tools lack sufficient sensitivity and specificity.
  • Bone biopsy is not widely available.

Conclusions:

  • Management of MBDs in kidney transplant recipients is complex.
  • Recent data offer improved insights into prevalence, pathophysiology, diagnosis, and treatment.
  • Further research is needed to refine diagnostic and therapeutic approaches.