Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

8.4K
The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
8.4K
Communication01:28

Communication

13.9K
Sharing information, concepts, and emotions to foster mutual understanding is communication. The sender, recipient, and transaction must be considered in this manner. The sender is the person who shares the message, the recipient is the person who receives and understands the message, and the transaction is the method used to deliver the message and the variables that affect the communication's context and surroundings. The nurse-client connection is built on therapeutic communication.
13.9K
Communication01:03

Communication

8.9K
Communication between two animals occurs when one animal transmits an information signal that causes a change in the animal that receives the information. Organisms communicate with one another in a host of different ways. Signals can be auditory, chemical, visual, tactile, or a combination of these. Communication is a critical behavioral adaptation that promotes survival, growth, and reproduction.
8.9K
Dose-Response Relationship: Overview01:03

Dose-Response Relationship: Overview

5.7K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
5.7K
Support Reactions01:30

Support Reactions

2.1K
A coplanar force system refers to a set of forces that all lie in the same plane and are subject to different reactions between the point of contact and the supports. Understanding how different types of supports affect coplanar forces is crucial for designing safe and reliable structures that can withstand external loads.
The purpose of the supports is to prevent the translational motion of the system by applying an equal and opposite force and to prevent the system's rotation by applying...
2.1K
Dose-Response Relationship: Potency and Efficacy01:22

Dose-Response Relationship: Potency and Efficacy

7.2K
The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sasanlimab taken together with Bacillus Calmette-Guérin (BCG) compared with BCG alone in people with high-risk non-muscle invasive bladder cancer: a plain language summary.

Future oncology (London, England)·2026
Same author

Stage- and smoking-associated microRNA expression in lung adenocarcinoma.

Translational lung cancer research·2025
Same author

Author Correction: Sasanlimab plus BCG in BCG-naive, high-risk non-muscle invasive bladder cancer: the randomized phase 3 CREST trial.

Nature medicine·2025
Same author

Nature-inspired metaheuristics for optimizing dose-finding and computationally challenging clinical trial designs.

Clinical trials (London, England)·2025
Same author

Phase II basket trial of Dual Anti-CTLA-4 and anti-PD-1 blockade in Rare Tumors (DART) SWOG S1609: pancreatic neuroendocrine neoplasm (PNEN) cohort.

Journal for immunotherapy of cancer·2025
Same author

Sasanlimab plus BCG in BCG-naive, high-risk non-muscle invasive bladder cancer: the randomized phase 3 CREST trial.

Nature medicine·2025
Same journal

RE:Electroacupuncture improves cognitive function and neuropsychiatric symptoms in breast cancer survivors: a pilot randomized controlled trial.

Journal of the National Cancer Institute·2026
Same journal

Worsening frailty and declining quality of life in older survivors of non-metastatic breast cancer.

Journal of the National Cancer Institute·2026
Same journal

Longitudinal effects of comorbidities on brain structure and cognition in older breast cancer survivors.

Journal of the National Cancer Institute·2026
Same journal

Response to Wang et al. and Shen et al.

Journal of the National Cancer Institute·2026
Same journal

Cluster randomized controlled trial of decision support for breast cancer chemoprevention, MiCHOICE.

Journal of the National Cancer Institute·2026
Same journal

Beyond R2: Assessing quality of trial level surrogate endpoints in colorectal cancer.

Journal of the National Cancer Institute·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE
06:57

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE

Published on: May 14, 2019

11.0K

Response

Denis L Jardim1, Maria Schwaederle1, J Jack Lee1

  • 1Department of Clinical Oncology, Hospital Sirio Libanes, Sao Paulo, Brazil (DFJ); Center for Personalized Cancer Therapy and Division of Hematology and Oncology, University of California, San Diego, CA, USA (MS and RZ); Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA (JJL and CW); The University of Texas MD Anderson Cancer Center, Houston, USA (JM); American Society of Clinical Oncology, Alexandria, VA, USA (RLS).

Journal of the National Cancer Institute
|February 26, 2016
PubMed
Summary

No abstract available in PubMed .

More Related Videos

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities
09:39

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities

Published on: October 3, 2008

17.3K
An Instrumented Pull Test to Characterize Postural Responses
12:18

An Instrumented Pull Test to Characterize Postural Responses

Published on: April 6, 2019

11.6K

Related Experiment Videos

Last Updated: Mar 25, 2026

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE
06:57

Modeling Verbal Behavior Deficits with the Stimulus Control Ratio Equation, SCoRE

Published on: May 14, 2019

11.0K
A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities
09:39

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities

Published on: October 3, 2008

17.3K
An Instrumented Pull Test to Characterize Postural Responses
12:18

An Instrumented Pull Test to Characterize Postural Responses

Published on: April 6, 2019

11.6K