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Mammalian Mitochondrial ncRNA Database.

Shanmugam Anandakumar1, Saravanan Vijayakumar2, Nagarajan Arumugam1

  • 1Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600 036, Tamil Nadu, India.

Bioinformation
|February 26, 2016
PubMed
Summary
This summary is machine-generated.

Mammalian Mitochondrial ncRNA is a new database for non-coding RNAs in mammals. It offers tools for searching, BLAST comparison, and retrieving data on ncRNA structure and function.

Keywords:
BLASTDatabasencRNA

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Area of Science:

  • Bioinformatics
  • Genomics
  • Molecular Biology

Background:

  • Non-coding RNAs (ncRNAs) play crucial roles in various biological processes.
  • Mammalian mitochondrial genomes contain unique ncRNAs that are underrepresented in existing databases.

Purpose of the Study:

  • To develop a comprehensive, user-friendly web-based database for mammalian mitochondrial non-coding RNAs (ncRNAs).
  • To provide integrated tools for data retrieval, analysis, and functional prediction of these ncRNAs.

Main Methods:

  • Database development using established bioinformatics pipelines.
  • Implementation of BLAST for sequence similarity searches.
  • Inclusion of tools for predicting RNA secondary structure and functional annotation.

Main Results:

  • The Mammalian Mitochondrial ncRNA database (MMNDB) is now publicly accessible.
  • The database offers efficient searching and comparison functionalities.
  • Detailed information on predicted structures and functions of mammalian ncRNAs is available.

Conclusions:

  • MMNDB serves as a valuable resource for researchers studying mammalian mitochondrial ncRNAs.
  • The database facilitates further investigation into the roles of these ncRNAs in cellular processes.
  • Accessible data and tools promote advancements in mitochondrial ncRNA research.