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Updated: Mar 25, 2026

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Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
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Gabriel Richet: the Man and the Scientist.
Summary
Professor Gabriel Richet pioneered French nephrology, performing early hemodialysis and transplantation. His research clarified acid-base balance, leaving a lasting legacy in kidney medicine.
Area of Science:
- Nephrology
- Medical History
Background:
- Gabriel Richet, a prominent figure in French medicine, hailed from a distinguished academic family.
- He demonstrated courage during WWII and actively participated in the French resistance, with family members deported during the German occupation.
Discussion:
- Richet co-founded French nephrology at Necker Hospital, conducting France's first hemodialysis and contributing to early organ transplantation.
- He led the nephrology department at Tenon Hospital from 1961 to 1985, fostering a collaborative environment for young scientists.
Key Insights:
- He identified the role of specialized collecting duct cells in regulating acid-base balance.
- Richet was a founding member and later President of the International Society of Nephrology.
Outlook:
- Richet's influence extended globally, evidenced by numerous international fellows and visiting faculty in his department.
- His retirement in 1985 marked the establishment of multiple nephrology departments led by his former trainees, solidifying his enduring legacy.
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