Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

11.1K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preserving scientific integrity in academic publishing: Navigating artificial intelligence, journal policies, and the impact factor as a quality indicator.

Osteoarthritis and cartilage open·2026
Same author

Transparency in reporting frameworks in Osteoarthritis and Cartilage Open: Research designs and value streams.

Osteoarthritis and cartilage open·2026
Same author

Preserving scientific integrity in academic publishing: Navigating artificial intelligence, journal policies, and the impact factor as a quality indicator.

Journal of ISAKOS : joint disorders & orthopaedic sports medicine·2026
Same author

Viral vector research in human gene therapy: Basic principles, alternative evaluation models, and clinical applications.

SLAS technology·2026
Same author

Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025.

Osteoarthritis and cartilage open·2026
Same author

Preserving scientific integrity in academic publishing: Navigating artificial intelligence, journal policies, and the impact factor as a quality indicator.

Journal of experimental orthopaedics·2026
Same journal

Smoking and lateral hinge fracture are associated with delayed union at 6 months in open wedge distal tibial tuberosity osteotomy.

Journal of experimental orthopaedics·2026
Same journal

Agreement of imageless navigation-derived pelvic tilt measurements with radiographic and CT-based measurements in direct anterior total hip arthroplasty: A prospective single-center study.

Journal of experimental orthopaedics·2026
Same journal

Medial open-wedge high tibial osteotomy demonstrates an 85.9% non-conversion rate and 76.8% patient satisfaction at a minimum follow-up of 10 years.

Journal of experimental orthopaedics·2026
Same journal

Measurement of intraarticular tibiofemoral rotation in routine MRI is not reliable: A comparison of knee joints in torsional and routine MRI.

Journal of experimental orthopaedics·2026
Same journal

Clavicle fractures and high-grade acromioclavicular joint injuries do not affect posture and thoracic kyphosis in young adults: A prospective comparative study.

Journal of experimental orthopaedics·2026
Same journal

Systematic reviews in PRP-augmented meniscal repair have limited methodological quality: A systematic overview.

Journal of experimental orthopaedics·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

1.5K

Translating orthopaedic basic science into clinical relevance.

Henning Madry1

  • 1Center of Experimental Orthopaedics, Saarland University, Homburg/Saar, D-66421, Germany. henning.madry@uks.eu.

Journal of Experimental Orthopaedics
|February 26, 2016
PubMed
Summary
This summary is machine-generated.

Experimental orthopaedics merges basic science and surgery to advance musculoskeletal health. This new discipline aims to translate research into effective treatments for orthopaedic conditions, improving patient outcomes.

Keywords:
Basic scienceClinicsOrthopaedicsTranslation

More Related Videos

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
18:40

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

Published on: October 16, 2014

17.9K
The Tibial Fracture-Pin Model: A Clinically Relevant Mouse Model of Orthopedic Injury
00:05

The Tibial Fracture-Pin Model: A Clinically Relevant Mouse Model of Orthopedic Injury

Published on: July 28, 2022

2.1K

Related Experiment Videos

Last Updated: Mar 25, 2026

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests
04:20

Author Spotlight: Enhancing Accuracy and Reproducibility in Whole Bone Bending Tests

Published on: September 1, 2023

1.5K
Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
18:40

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

Published on: October 16, 2014

17.9K
The Tibial Fracture-Pin Model: A Clinically Relevant Mouse Model of Orthopedic Injury
00:05

The Tibial Fracture-Pin Model: A Clinically Relevant Mouse Model of Orthopedic Injury

Published on: July 28, 2022

2.1K

Area of Science:

  • Orthopaedics and Trauma Surgery
  • Biomedical Research
  • Musculoskeletal System Science

Background:

  • Biomedical research has significantly advanced the understanding of the musculoskeletal system.
  • A new discipline, experimental orthopaedics, integrates basic science with surgical practice.
  • This field shows potential for developing causative cures for various orthopaedic conditions.

Purpose of the Study:

  • To bridge the gap between orthopaedic basic science and clinical application.
  • To facilitate the translation of significant research findings into clinical practice.
  • To advance the understanding and treatment of the entire musculoskeletal system.

Main Methods:

  • Integration of rigorous basic science research.
  • Application of advanced musculoskeletal surgical techniques.
  • Focus on translational research for clinical relevance.

Main Results:

  • Establishment of experimental orthopaedics as a distinct discipline.
  • Identification of promising avenues for causative cures in orthopaedics.
  • Foundation for translating research into improved patient care.

Conclusions:

  • Experimental orthopaedics is a rapidly evolving field with significant potential.
  • Translational research is key to realizing the full clinical benefits of basic science discoveries.
  • The Journal of Experimental Orthopaedics aims to foster this crucial link for the musculoskeletal system.