Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal GGT Trajectories Identify Prognostic Phenotypes in Paediatric Primary Sclerosing Cholangitis.

JHEP reports : innovation in hepatology·2026
Same author

Does Gamma Knife Stereotactic Radiosurgery Preserve Hearing on Short- and Long-Term Follow-Up?

The Laryngoscope·2026
Same author

Otological conditions and autism spectrum disorder in Medicaid beneficiaries aged 1 to 20 years: a cross-sectional study.

BMC pediatrics·2026
Same author

Processing-Driven Control of the Properties of Polymer Grafted Nanoparticle Composites.

ACS nano·2026
Same author

Multi-Task Assessment of Context-Specific Gait Changes to Virtual Reality-Based Visual Perturbations.

The Laryngoscope·2026
Same author

Reply: comment on "Superior semicircular abnormalities are more common in patients presenting to the emergency room with unexplained vertigo".

Clinical imaging·2026
Same journal

Superelastic Ti-Zr-Nb-Sn Thin Films Fabricated by Magnetron Sputtering: Biocompatibility and Bacterial Biofilm Formation Assessment for Orthopedic Applications.

Journal of biomedical materials research. Part A·2026
Same journal

Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion.

Journal of biomedical materials research. Part A·2026
Same journal

ROS-Responsive Quercetin Nanoparticles Improve the Prognosis of Traumatic Brain Injury by Inhibiting Aberrant Nrf2-Keap1 Signaling Pathway Activation.

Journal of biomedical materials research. Part A·2026
Same journal

Cellular Insights Into Proangiogenic Activation in Fibroblast and Endothelial Cells by Dual Drug-Loaded Emulsion Electrospun Nanofibers for Enhanced Tissue Regeneration.

Journal of biomedical materials research. Part A·2026
Same journal

Biomimetic Collagen Scaffolds Natural Cross-Linking Strategies via Transglutaminase and Methylglyoxal for Skin Repair.

Journal of biomedical materials research. Part A·2026
Same journal

Granular Hydrogel Composites for Noninvasive Optical Biosensing.

Journal of biomedical materials research. Part A·2026
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Author Spotlight: Enhancing Microinjection Needle Quality by Wet Beveling
06:00

Author Spotlight: Enhancing Microinjection Needle Quality by Wet Beveling

Published on: September 27, 2024

919

Serrated needle design facilitates precise round window membrane perforation.

James P Stevens1, Hirobumi Watanabe1,2, Jeffrey W Kysar2

  • 1Department of Otolaryngology-Head and Neck Surgery, Columbia University College of Physicians and Surgeons, New York, New York.

Journal of Biomedical Materials Research. Part A
|February 26, 2016
PubMed
Summary
This summary is machine-generated.

A novel multi-serrated needle precisely perforates the round window membrane (RWM) for cochlear implantation. This tool minimizes inner ear trauma and intracochlear pressure fluctuations, improving surgical outcomes.

Keywords:
cochlear implant electrode insertioncochlear implantationcrown needleelectron discharge machininground window membrane

More Related Videos

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane
07:32

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

Published on: March 16, 2015

17.4K
Author Spotlight: Extraction of Guinea Pig Round Window Membrane to Facilitate Inner Ear Drug Delivery Research
05:14

Author Spotlight: Extraction of Guinea Pig Round Window Membrane to Facilitate Inner Ear Drug Delivery Research

Published on: February 23, 2024

1.2K

Related Experiment Videos

Last Updated: Mar 25, 2026

Author Spotlight: Enhancing Microinjection Needle Quality by Wet Beveling
06:00

Author Spotlight: Enhancing Microinjection Needle Quality by Wet Beveling

Published on: September 27, 2024

919
Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane
07:32

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane

Published on: March 16, 2015

17.4K
Author Spotlight: Extraction of Guinea Pig Round Window Membrane to Facilitate Inner Ear Drug Delivery Research
05:14

Author Spotlight: Extraction of Guinea Pig Round Window Membrane to Facilitate Inner Ear Drug Delivery Research

Published on: February 23, 2024

1.2K

Area of Science:

  • Biomedical Engineering
  • Otolaryngology
  • Materials Science

Background:

  • The round window membrane (RWM) is the preferred cochlear implant electrode insertion site, minimizing inner ear trauma.
  • Current RWM perforation methods cause tearing and pressure fluctuations due to a lack of specialized tools.

Purpose of the Study:

  • To design and evaluate a multi-serrated needle for precise RWM perforation.
  • To minimize RWM tearing and intracochlear pressure fluctuations during cochlear implantation.

Main Methods:

  • Designed and manufactured four- and eight-serrated needles using wire electrical discharge machining (EDM).
  • Tested needle perforation efficacy on human temporal bones using a micromanipulator.
  • Analyzed RWM perforations using light and scanning electron microscopy (SEM).

Main Results:

  • Serrated needles created consistent, appropriately sized RWM perforations with minimal tearing.
  • The octagonal (eight-serrated) needle produced preferred smooth oval holes.
  • Needles demonstrated durability for repeated use, though designed for single use.

Conclusions:

  • Multi-serrated needles offer a precise method for RWM perforation, reducing surgical trauma.
  • The octagonal needle design is superior for creating optimal oval perforations in the RWM.
  • This innovation enhances safety and efficacy in cochlear implantation procedures.