Related Experiment Video
Updated: Mar 25, 2026

An Automated T-maze Based Apparatus and Protocol for Analyzing Delay- and Effort-based Decision Making in Free Moving Rodents
Published on: August 2, 2018
The LATER model of reaction time and decision
Imran Noorani1, R H S Carpenter1
1Department of Physiology, Development and Neuroscience, University of Cambridge, UK.
Abstract:
How do we choose one option rather than another when faced with uncertainty about the information we receive, and the consequences of what we decide? The LATER (Linear Approach to Threshold with Ergodic Rate) model has proved to be remarkably accurate in predicting how we respond in such situations. Given its conceptual simplicity, its grounding in fundamental Bayesian principles and its very few free parameters, it is being increasingly adopted for a wider range of choice tasks, helping us to understand the underlying neural mechanisms, and in applying this to clinical disorders. Here, we provide a thorough discussion of the history behind this model, and how it can be applied to more complex decisions, including anti-saccades, Go-NoGo, countermanding and other situations where newly-arriving information means that ongoing decisions must be modified. The neuroscience of decision-making is progressing rapidly, and we anticipate that wider understanding and application of this model will help simplify the interpretation of increasingly advanced decision behaviour both in the laboratory and clinic.
Related Concept Videos
Reason and Intuition
Decision Making
Automatic decision-making is fast, intuitive, and relies on gut feelings...
Pharmacodynamic Models: Direct Effect Model and Indirect Response Model
Decision Making: Traditional Method
First, a specific claim about the population parameter is decided based on the research question and is stated in a simple form. Further, an opposing statement to this claim is also stated. These statements can act as null and alternative hypotheses, out of which a null hypothesis would be a...
Pharmacodynamic Models: Link Model and Systems Pharmacodynamic Model
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

