Clinical experience with ciprofloxacin: analysis of a multicenter study

Area of Science:

• Pharmacology
• Infectious Diseases

Background:

• Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used for various bacterial infections.
• Assessing the real-world effectiveness and safety of ciprofloxacin is crucial for clinical practice.

Purpose of the Study:

• To evaluate the efficacy and safety of ciprofloxacin in a multicenter patient cohort.
• To determine bacteriologic and clinical outcomes, as well as the incidence of adverse reactions.

Main Methods:

• A multicenter study involving 90 patients treated with ciprofloxacin.
• Analysis of microbiologically proven infections and reported treatment outcomes.
• Documentation of adverse reactions and reasons for therapy discontinuation.

Main Results:

• High rates of bacteriologic cure (92.7%) and clinical cure (88.4%) were observed.
• Low incidence of treatment failure (2.3%) and adverse reactions (10%).
• Ciprofloxacin discontinuation due to adverse effects occurred in 4.4% of patients.

Conclusions:

• Ciprofloxacin is an effective and generally well-tolerated antibiotic for a range of infections.
• The study supports the use of ciprofloxacin in clinical settings based on its favorable efficacy and safety profile.