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Methodologies for medication adherence evaluation: Focus on psoriasis topical treatment.

Ana Teixeira¹, Maribel Teixeira², Vera Almeida²

¹CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Rua Central de Gandra 1317, 4585-116 Gandra PRD, Portugal; Laboratório de Tecnologia Farmacêutica, Departamento de Ciências do Medicamento, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira n° 228, 4050-313 Porto, Portugal.

Journal of Dermatological Science

|February 27, 2016

Summary

Evaluating topical treatment adherence in psoriasis is crucial. A systematic review found questionnaires variable and medication weight methods complex, recommending combined approaches for better adherence measurement.

Keywords:

Adherence methodologies Psoriasis Topical medicines Treatment adherence

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Area of Science:

Dermatology
Pharmacology
Health Services Research

Background:

Adherence to topical treatments is less understood than systemic therapies.
High-quality research is needed to improve medication adherence and clinical outcomes in psoriasis patients.
Current understanding of topical treatment adherence evaluation is limited.

Purpose of the Study:

To systematically review methodologies for evaluating topical treatment adherence in psoriasis.
To identify the most common and effective methods for assessing adherence to topical psoriasis treatments.
To provide recommendations for improving the assessment of topical treatment adherence.

Main Methods:

Systematic review of 21 studies evaluating topical treatment adherence in psoriasis.
Analysis of six different adherence measurement methodologies used across selected studies.
Assessment of the frequency and variability of different adherence measurement techniques.

Main Results:

Questionnaires were the most frequently used method (44%) but showed high variability in results.
Only three studies utilized multiple adherence measurement methods.
Medication weight measurement, while considering applied dose, was complex and less effective without modifications.
Lack of validated questionnaires specific to topical treatment adherence was noted.

Conclusions:

No single method accurately assesses topical treatment adherence comprehensively.
A combination of methods, including self-report and medication weight measurements, is recommended.
Future research should focus on developing validated tools and standardized methods for topical adherence assessment.