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West Nile Virus Infection in the Central Nervous System

Evandro R Winkelmann1, Huanle Luo1, Tian Wang2

  • 1Department of Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas, 77555, USA.

F1000Research
|February 27, 2016
PubMed

Keywords:
West Nile Virusarboviral encephalitiscentral nervous system infectionflaviviruswest nile virus infection in central nervous system

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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