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Related Concept Videos

Continuous Renal Replacement Therapy01:30

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Acute Kidney Injury V: Interprofessional Care01:20

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
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Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

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Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
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Year in review 2012: Critical Care--Nephrology.

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Related Experiment Video

Updated: Mar 25, 2026

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
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Renal Replacement Therapy.

Zaccaria Ricci1, Stefano Romagnoli2, Claudio Ronco3

  • 1Department of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, Rome, Italy.

F1000Research
|February 27, 2016
PubMed
Summary
This summary is machine-generated.

Critically ill patients often develop acute kidney injury, requiring renal replacement therapy (RRT). Advances in dialysis technology and personalized treatment strategies improve outcomes for these complex cases.

Keywords:
Renal Replacement Therapyacute kidney injuryanticoagulation strategiesblood purificationcritical care nephrologydialysis

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Area of Science:

  • Nephrology
  • Critical Care Medicine
  • Intensive Care Unit (ICU) Management

Background:

  • Increasing severity of diseases in critically ill patients leads to multiorgan dysfunction.
  • Acute kidney injury (AKI) is a common complication in intensive care units (ICUs).
  • Renal replacement therapies (RRT) are essential for managing AKI in critically ill patients.

Purpose of the Study:

  • To provide a comprehensive overview of current practices in RRT for critically ill patients.
  • To address key clinical aspects of RRT, including dosing, modality, anticoagulation, and timing.
  • To cover technical considerations and clarify nomenclature in critical care nephrology.

Main Methods:

  • Review of current literature and clinical practices in RRT for critically ill patients.
  • Discussion of technological advancements in dialysis machines and their applications.
  • Analysis of factors influencing individualized RRT prescription, such as sepsis and fluid overload.

Main Results:

  • Technological improvements have resulted in safer, more versatile, and efficient dialysis machines.
  • Emerging evidence supports individualized RRT prescriptions tailored to patient-specific clinical conditions.
  • Standardization of nomenclature is needed to improve clarity in critical care nephrology.

Conclusions:

  • Renal replacement therapy is a routine and vital component of critical care for patients with acute kidney injury.
  • Personalized treatment approaches and advanced technology enhance the effectiveness of RRT.
  • Further clarification of RRT nomenclature is necessary for consistent communication and practice.