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Immune regulation in IgA nephropathy
R C Monteiro1, L H Noël, A Chevailler
1Département de Néphrologie et INSERM U 25, Hôpital Necker, Paris.
Nephrologie
|January 1, 1989
Abstract:
Regulation in IgA nephropathy (IgA N) has been largely studied. We present in this work our recent data which suggest that an abnormal chemical structure and/or molecular form of serum immunoglobulin A (IgA) might contribute to both the mesangial deposition of IgA and the T cell abnormalities which may in turn deregulate the IgA synthesis.