[Muscle biopsy--sampling and preparation of muscle fiber bundles]

Biopsy pathology of muscle will be useful in the diagnoses of neuromuscular diseases. Techniques used for muscle biopsy provide muscle tissue in order to obtain high quality of histological and ultrastructural preparations and tissue for biochemical investigations. Therefore muscle should be obtained by open biopsy fulfilling anatomical conditions. Experiences received in about 500 open biopsies are reported.