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Fibromyalgia Pathogenesis and Treatment Options Update
Steven Chinn1, William Caldwell1, Karina Gritsenko2
1Department of Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Current Pain and Headache Reports
|February 29, 2016
Summary
Fibromyalgia is a complex chronic pain condition affecting the central nervous system. This review covers its diagnosis, symptoms, causes, and evidence-based treatments, including medications and therapies.
Area of Science:
- Rheumatology
- Neuroscience
- Pain Management
Background:
- Fibromyalgia is a chronic condition characterized by widespread pain and other symptoms.
- Understanding its complex pathophysiology is crucial for effective management.
Purpose of the Study:
- To review current literature on fibromyalgia.
- To summarize diagnostic criteria, clinical features, pathophysiology, risk factors, and treatment options.
Main Methods:
- Literature review of up-to-date research on fibromyalgia.
- Synthesis of information on diagnostic criteria, clinical manifestations, pathogenesis, and therapeutic interventions.
Main Results:
- Recent diagnostic criteria from the American College of Rheumatology are presented.
- Key clinical features include chronic pain, hyperalgesia, mood disorders, anxiety, and sleep disturbances.
- Pathophysiology involves central and peripheral nervous system alterations, with genetic and environmental factors contributing.
Conclusions:
- Fibromyalgia management requires a comprehensive approach.
- Treatment options include established and investigational pharmacological agents, alongside non-pharmacological therapies like exercise and acupuncture.
Keywords:
Central sensitivity syndromeFibromyalgiaFibromyalgia, acupunctureFibromyalgia, massageFibromyalgia, pathogenesisFibromyalgia, sleep disturbanceFibromyalgia, treatmentMore Related Videos
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