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Depressive Symptoms and Risk of Postoperative Delirium
Patrick J Smith1, Deborah K Attix2, B Craig Weldon3
1Psychiatry and Behavioral Sciences, Division of Medical Psychology, Duke University Medical Center, Durham, NC.
Summary
Behavioral inactivity, a component of depression, significantly increases the risk of postoperative delirium. Other depression facets like negative affect and cognitive distress did not show this association in surgical patients.
Area of Science:
- Geriatric Medicine
- Neuroscience
- Psychiatry
Background:
- Elevated depressive symptoms are linked to a higher risk of postoperative delirium.
- Previous research has not explored if specific depression components differentially predict delirium.
Purpose of the Study:
- To investigate whether distinct components of depression predict postoperative delirium.
- To identify specific depression facets associated with increased delirium risk in surgical patients.
Main Methods:
- 1020 patients were assessed for postoperative delirium using the Confusion Assessment Method and chart review.
- Preoperative assessments included cognitive, psychosocial, and medical evaluations.
- Depression was measured using the Geriatric Depression Scale-Short Form.
Main Results:
- 3.7% of patients developed delirium.
- Behavioral inactivity, a depression component, was significantly associated with increased delirium risk (OR: 1.95).
- Negative affect and cognitive distress components of depression were not significantly linked to delirium risk.
Conclusions:
- Different components of depression have varying predictive power for postoperative delirium.
- Behavioral inactivity is a key predictor of delirium in adults undergoing noncardiac surgery.
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