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[Chronic kidney disease and nutrition]
Takuya Yoshida1, Hiromichi Kumagai1
1Department of Clinical Nutrition, School of Food and Nutritional Sciences, University of Shizuoka, Japan.
Clinical Calcium
|March 1, 2016
Summary
Chronic kidney disease (CKD) mineral and bone disorder (CKD-MBD) involves mineral metabolism abnormalities. Early intervention in CKD-MBD is crucial for managing mineral levels and bone health.
Area of Science:
- Nephrology
- Endocrinology
- Mineral Metabolism
Context:
- Mineral metabolism abnormalities are common in chronic kidney disease (CKD).
- These abnormalities define CKD-mineral and bone disorder (CKD-MBD).
- Standard management aims to normalize serum phosphorus, calcium, and parathyroid hormone levels.
Purpose:
- To highlight the importance of early intervention in managing CKD-MBD.
- To emphasize the role of dietary and medication management.
- To underscore the link between declining renal function and mineral imbalances.
Summary:
- CKD-MBD encompasses disruptions in mineral and bone metabolism linked to reduced kidney function.
- Current treatment strategies focus on maintaining reference ranges for key minerals and hormones.
- Emerging evidence suggests that initiating CKD-MBD treatment in the early stages of CKD is vital.
Impact:
- Early management can potentially slow CKD-MBD progression.
- Optimizing mineral balance may improve patient outcomes in CKD.
- This underscores the need for proactive therapeutic approaches in nephrology.
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