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Related Concept Videos

Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

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Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
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Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Cognitive Therapy01:25

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Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
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[Corticotherapy and suicidal behavior: A case report].

G Carle1, G Abgrall-Barbry1

  • 1Département de psychiatrie, psychotraumatisme et addictions, CHU Tenon, 4, rue de la Chine, 75020 Paris, France; Université Pierre-et-Marie-Curie, 15, rue de l'École-de-médecine, 75006 Paris, France.

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PubMed
Summary
This summary is machine-generated.

Corticosteroids may precipitate suicidal behavior, especially in patients with undiagnosed depression. Early psychiatric screening and awareness of this risk are crucial for patient safety during steroid treatment.

Keywords:
CorticosteroidCorticoïdesDépressionIntoxication médicamenteuseMultiple sclerosisSclérose en plaquesSide effectSteroid-induced psychiatric disordersSuicide attemptTentative de suicide

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Pharmacology

Background:

  • Suicide attempts are a significant public health issue, with iatrogenic factors contributing.
  • Corticosteroids are associated with psychiatric side effects, but steroid-induced suicidal behavior is poorly understood.
  • Previous studies suggest 5.7% of patients on corticosteroids develop psychiatric disorders, with limited data on suicidality.

Observation:

  • A 50-year-old woman with multiple sclerosis developed major depressive disorder symptoms during intravenous methylprednisolone treatment.
  • Two weeks after a five-day course of methylprednisolone, she attempted suicide via prescription drug overdose.
  • Her suicidal behavior is hypothesized to be a transient, acute reaction linked to high-dose corticosteroid use.

Findings:

  • Corticosteroids may precipitate suicidal behavior in individuals with undiagnosed premorbid depressive disorders.
  • A correlation between corticosteroid treatment and suicidal behavior is supported by recent longitudinal studies.
  • Neurobiological mechanisms may explain the link between corticosteroid therapy and increased suicidality.

Implications:

  • Early screening for psychiatric disorders before initiating corticosteroid therapy is essential.
  • Physicians and patients must be aware of the potential risk of increased suicidality with corticosteroid use.
  • Management may involve tapering corticosteroids and initiating antidepressant treatment, though strategies require further research.