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Ex vivo Expansion of Tumor-reactive T Cells by Means of Bryostatin 1/Ionomycin and the Common Gamma Chain Cytokines Formulation
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Published on: January 14, 2011

Effect of insulin on the production of interleukin 2 by T lymphocytes

Y Luo, Z H Feng, R D Wang

    Zhongguo Yao Li Xue Bao = Acta Pharmacologica Sinica
    |May 1, 1989
    PubMed

    The effect of insulin on interleukin 2 (IL-2) production was investigated. The results showed that insulin alone did not stimulate the resting T lymphocytes to produce IL-2, but enhanced the production of IL-2 by T lymphocytes and interleukin 1 (IL-1) by macrophages in the presence of lectin. Insulin augmented the response of T lymphocytes to IL-1 in the presence of Con A. The peak time of IL-2 production was not affected by insulin.

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