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Molecular identification of emergent GII.P17-GII.17 norovirus genotype, Romania, 2015

Sorin Dinu1, Mariana Nagy, Dana Gabriela Negru

  • 1Molecular Epidemiology Laboratory, Cantacuzino National Institute of Research, Bucharest, Romania.

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|March 1, 2016
PubMed

Insights

The GII.P17-GII.17 norovirus strain, a cause of gastroenteritis outbreaks, was identified in Romania in 2015. This emergent strain has been increasingly reported globally since 2014/15.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The GII.P17-GII.17 norovirus genotype emerged globally during the 2014/15 winter season.
  • This novel genotype has replaced the previously pandemic GII.4 Sydney 2012 strain in causing gastroenteritis outbreaks.
  • Sporadic reports of GII.P17-GII.17 have occurred outside of Asia.

Purpose of the Study:

  • To report the identification of the GII.P17-GII.17 norovirus genotype in Romania.
  • To document the occurrence of this emergent strain during a large acute gastroenteritis outbreak.

Main Methods:

  • Case identification during a large outbreak.
  • Norovirus genotyping of clinical isolates.

Main Results:

  • A significant outbreak of acute gastroenteritis affected 328 individuals in Romania in 2015.
  • GII.P17-GII.17 norovirus isolates, similar to the Kawasaki308 2015 strain, were identified in three patients.
  • This marks the first reported identification of this emergent genotype in Romania.

Conclusions:

  • The GII.P17-GII.17 norovirus genotype has established a presence in Europe.
  • Continued surveillance is crucial to monitor the spread of emergent norovirus strains globally.
Keywords:
CaliciviridaeGII.P17-GII.17emergent genotypemolecular typingnorovirusviral gastroenteritis

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