Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Human Microbiota01:30

Development of Human Microbiota

14
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
14
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

78.6K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
78.6K
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

34
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
34
Microbiota of the Large Intestine01:27

Microbiota of the Large Intestine

8
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
8
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

19
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
19
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

14
The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
14

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Additional benefit of standardized computed tomography-based lymph node assessment utilizing Node-RADS in esophageal adenocarcinoma.

ESMO gastrointestinal oncology·2026
Same author

Zeitschrift fur Gastroenterologie·2024
Same author

Zeitschrift fur Gastroenterologie·2023
Same author

Inflammatory Bowel Disease Management During the COVID-19 Outbreak: The Ten Do's and Don'ts from the ECCO-COVID Taskforce.

Journal of Crohn's & colitis·2020
Same author

[Transition medicine].

Der Internist·2018
Same author

[Transition medicine-structural solutions].

Der Internist·2018

Related Experiment Video

Updated: Mar 25, 2026

Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

5.9K

Faecal microbiota transplantation-A clinical view.

J Mattner1, F Schmidt2, B Siegmund2

  • 1Mikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen, Wasserturmstraße 3-5, 91054 Erlangen, Germany.

International Journal of Medical Microbiology : IJMM
|March 1, 2016
PubMed
Summary

Faecal microbiota transplantation shows promise for inflammatory bowel disease, with early success in ulcerative colitis remission. However, further research is needed to understand donor selection and potential risks like obesity transfer.

Keywords:
Clostridium difficileFaecal microbiota transplantationInflammatory bowel diseaseMicrobiotaObesity

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

3.6K
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.8K

Related Experiment Videos

Last Updated: Mar 25, 2026

Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

5.9K
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

3.6K
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.8K

Area of Science:

  • Gastroenterology and Microbiome Research
  • Fecal Microbiota Transplantation (FMT) applications

Background:

  • Fecal microbiota transplantation (FMT) is increasingly studied for transferring phenotypes between individuals.
  • Currently, FMT's only FDA-approved indication is refractory Clostridium difficile infection, despite ongoing research questions.

Purpose of the Study:

  • To explore the potential of FMT as a therapeutic approach for inflammatory bowel disease (IBD).
  • To review current understanding of FMT's impact on microbiota composition and clinical outcomes in IBD.

Main Methods:

  • Review of existing studies investigating FMT in animal models and human clinical trials for IBD.
  • Analysis of data on changes in intestinal microbiota composition post-FMT in relation to inflammation levels.

Main Results:

  • FMT can alter intestinal microbiota composition, with effects varying based on inflammation severity.
  • Preliminary data suggest that optimized microbiota transplantation may induce clinical remission in ulcerative colitis.
  • FMT can transfer not only therapeutic effects but also risk factors, such as obesity.

Conclusions:

  • While FMT shows potential for IBD treatment, particularly ulcerative colitis, significant questions remain.
  • Further research is crucial to identify optimal donors, transplant mixtures, and administration routes.
  • A comprehensive understanding of microbiota's impact is necessary before designing standardized FMT protocols.