Random-walk chemotaxis: trial and error as a control process

The biased random-walk chemotaxis of the bacterium Escherichia coli is a remarkably effective method of navigation based on random trial-and-error responding rather than steering. Humans restricted to the same mode of responding are able to navigate to target locations, just like the bacterium. This mode of navigation can be modeled as an input control process that selectively retains favorable and rejects unfavorable consequences of the random responses. The selection process is determined by the internal organization of the system rather than the external influence of the environment (as in natural selection or reinforcement).