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Outcome Analysis of Asymptomatic Lower Pole Stones in Children
Joana Dos Santos1, Roberto Iglesias Lopes1, Ana Oliveira Veloso1
1Division of Urology, Department of Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; Division of Nephrology, Department of Pediatrics (EH), The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Insights
Most asymptomatic lower pole renal stones in children can be monitored conservatively. Larger initial stone size and stone growth over time predict the need for intervention in pediatric kidney stones.
Area of Science:
- Pediatric Nephrology
- Urology
- Medical Imaging
Background:
- Lower pole renal stones in children often present incidentally.
- The frequency and intervention rates for asymptomatic pediatric lower pole stones are not well-established.
Purpose of the Study:
- To evaluate the outcomes of asymptomatic, incidentally detected lower pole renal stones in children.
- To determine the frequency and need for intervention in this patient group.
Main Methods:
- Retrospective chart and renal ultrasound review of pediatric patients with lower pole stones over 14 years.
- Statistical analysis (unpaired t-test) to identify predictors of intervention, including stone size, growth, type, and metabolic disease.
- Calculation of nonoperative management success rate (spontaneous passage or stability without symptoms).
Main Results:
- 224 children with lower pole stones were identified; 53.6% spontaneously passed stones.
- 25% of stones remained asymptomatic and stable.
- Intervention was required in 21.4% of cases. Larger baseline size (median 7 mm vs 5 mm) and stone growth predicted intervention needs.
Conclusions:
- Asymptomatic lower pole renal stones in children can be managed conservatively.
- Approximately 78.6% of stones either passed spontaneously or remained asymptomatic and stable.
- Initial stone size >7 mm and evidence of stone growth are significant predictors for requiring intervention.
Purpose:
Lower pole renal stones in children usually present incidentally. To our knowledge frequency and need for intervention are unknown. We evaluated the outcomes of asymptomatic, incidentally found lower pole renal stones in children.
Materials And Methods:
We retrospectively reviewed the charts and renal ultrasounds of children with lower pole stones seen during a period of 14 years. The unpaired t-test was used to determine factors that might predict the need for stone intervention, including size, growth rate, type of stone and underlying metabolic disease. The success rate of nonoperative management, defined by spontaneous passage or lack of growth in the absence of symptoms, was calculated.
Results:
A total of 224 children were found to have lower pole stones. Mean ± SD age at presentation was 95.2 ± 65.3 months. Of the patients 120 (53.6%) spontaneously passed stones. Of the stones 25% remained asymptomatic and did not grow with time. Intervention was performed in 48 children (21.4%). Stones originally managed conservatively that later required intervention were significantly larger at baseline than stones that did not require intervention through the end of followup (median 7 vs 5 mm, p <0.001) and those that grew with time (median stone size 8 mm at surgical intervention, p = 0.01).
Conclusions:
Our data suggest that asymptomatic lower pole renal stones can be followed conservatively. Of the calculi 78.6% passed spontaneously or remained asymptomatic and did not grow. Median initial size greater than 7 mm and stone growth with time were significant risk factors that predicted the need for intervention.
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