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Published on: May 6, 2018
[Contrast-induced nephropathy: An update]
V Spagnoli1, L Azzalini1, V X Tadros1
1Université de Montréal, Interventional Cardiology Division, Department of Medicine, Montreal Heart Institute, 5000 Bélanger street, Montréal, H1T 1C8 QC, Canada.
Insights
Contrast-induced nephropathy (CIN) is a frequent complication in hospitalized patients, increasing healthcare costs and mortality. This review examines CIN
Area of Science:
- Nephrology
- Radiology
- Cardiology
Background:
- Contrast-induced nephropathy (CIN) is a significant clinical problem in hospitalized patients.
- CIN is linked to extended hospital stays, increased costs, and higher morbidity and mortality rates.
- Patients undergoing cardiac catheterization are particularly susceptible to CIN due to underlying health conditions.
Purpose of the Study:
- To review the definition, pathophysiology, diagnosis, and preventive strategies for CIN.
- To summarize the properties of iodinated contrast media relevant to CIN.
Main Methods:
- Literature review focusing on CIN definition, pathophysiology, diagnosis, and prevention.
- Summary of iodinated contrast medium properties.
Main Results:
- CIN definition and pathophysiology were reviewed.
- Diagnostic approaches for CIN were summarized.
- Various preventive strategies for CIN were discussed.
Conclusions:
- Effective preventive strategies for CIN are crucial, especially for high-risk patients.
- Understanding contrast medium properties aids in CIN prevention.
- Further research into optimal CIN prevention is warranted.
Abstract:
Contrast-induced nephropathy (CIN) is common in hospitalized patients. Its occurrence is associated with an increased hospitalization stay and cost, morbidity and mortality. Thus, preventives strategies remain a major issue. Patients that are referred for cardiac catheterization are among the most vulnerable to develop CIN due to their comorbidities. Moreover, in some cases, such preventives measures cannot be introduced due to emergent clinical settings. After a summary regarding the properties of iodinated contrast medium, the aim of this work was to review the definition, pathophysiology, diagnosis and preventive strategies related to CIN.
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