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Updated: Mar 24, 2026

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
Published on: April 1, 2019
[Tissue engineering applied to the trachea as a graft]
Elisa Barrera-Ramírez1, Edna Rico-Escobar1, Rubén E Garrido-Cardona1,2
1Departamento de Ciencias de la Salud, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Centro Médico de Especialidades de Ciudad Juárez, Ciudad Juárez, Chihuahua, Chih., México.
Abstract:
Tissue engineering offers, through new technologies, an ex vivo generation of organs and functional tissues as grafts for transplants, for the improvement and substitution of biological functions, with an absence of immunological response. The treatment of extended tracheal lesions is a substitution of the affected segment; nevertheless, the allogeneic transplant has failed and the use of synthetic materials has not had good results. New tissue engineering technology is being developed to offer a tracheal graft for a posterior implantation. The purpose of this article is to review all the methods and components used by the engineering of tissue for tracheal grafts.
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