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Related Concept Videos

Trachea01:22

Trachea

6.1K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
6.1K
Tracheostomy: Procedure and Tubes01:28

Tracheostomy: Procedure and Tubes

4.8K
A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
4.8K
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

2.4K
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
2.4K

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Related Experiment Video

Updated: Mar 24, 2026

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
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Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

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[Tissue engineering applied to the trachea as a graft].

Elisa Barrera-Ramírez1, Edna Rico-Escobar1, Rubén E Garrido-Cardona1,2

  • 1Departamento de Ciencias de la Salud, Instituto de Ciencias Biomédicas, Universidad Autónoma de Ciudad Juárez, Centro Médico de Especialidades de Ciudad Juárez, Ciudad Juárez, Chihuahua, Chih., México.

Gaceta Medica De Mexico
|March 2, 2016
PubMed
Summary

Tissue engineering aims to create ex vivo grafts for transplants, avoiding immune responses. This review explores tissue engineering methods for tracheal grafts, addressing limitations of current treatments.

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Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

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Related Experiment Videos

Last Updated: Mar 24, 2026

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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
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Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

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Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Translational Medicine

Context:

  • Tracheal reconstruction presents challenges due to the failure of allogeneic transplants and synthetic materials.
  • Extended tracheal lesions require innovative solutions for functional restoration.
  • Tissue engineering offers a promising alternative for creating functional tracheal grafts.

Purpose:

  • To comprehensively review current methods and components utilized in tissue engineering for tracheal grafts.
  • To highlight advancements in ex vivo tissue generation for tracheal repair.
  • To provide an overview of the state-of-the-art in tracheal tissue engineering.

Summary:

  • This article reviews tissue engineering strategies for developing tracheal grafts.
  • It examines various methods and essential components for ex vivo generation of tracheal tissues.
  • The focus is on creating functional grafts that overcome limitations of current treatments.

Impact:

  • Facilitates the development of improved tracheal grafts for transplantation.
  • Addresses the unmet need for effective treatments for extensive tracheal damage.
  • Advances the field of regenerative medicine for complex organ substitution.