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Updated: Mar 24, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
Stratification and Risk Reduction of Perioperative Acute Kidney Injury
Selma Ishag1, Charuhas V Thakar2
1Division of General Anesthesiology, Barnes-Jewish Hospital, Washington University, South Campus, Campus Box 8054, 660 South Euclid Avenue, St Louis, MO 63110-1093, USA.
Abstract:
Perioperative acute kidney injury (AKI) is associated with an increased morbidity and mortality. The incidence of AKI varies depending on preoperative risk factors and the surgical setting. Preoperative risk stratification is critical for informed consent and perioperative planning. Perioperative renal protection strategies are potentially invaluable in the prevention of AKI. Current advances in the development of biomarkers may offer the opportunity for early diagnosis and the implementation of therapeutic strategies. Increased awareness and concerted efforts by all perioperative physicians are needed to provide an improved outcome for surgical patients.
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