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Updated: Mar 24, 2026

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Michael Joseph Barrett1, Peter Leslie John Barnett
1*Department of Emergency Medicine, Royal Children's Hospital, Melbourne, Victoria, Australia; †Research Fellow (M. Barrett), Paediatric Emergency Research Unit, National Children's Research Centre, Dublin, Ireland; ‡Clinical Researcher (M. Barrett) and Honorary Research Fellow (P. Barnett), Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia; §Department of Emergency Medicine, Our Lady's Children's Hospital, Dublin, Ireland; and ∥Clinical Associate Professor (P. Barnett), University of Melbourne, Melbourne, Victoria, Australia.
Complex Regional Pain Syndrome Type 1 (CRPS1) in children presents with disproportionate limb pain and autonomic dysfunction. Early diagnosis and a multidisciplinary treatment approach focusing on function and pain relief lead to favorable outcomes.
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