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Thirteen-And-A-Half Syndrome.

Daniel S Allbon¹, Ben La Hood

¹Department of Ophthalmology, Dunedin Hospital, Dunedin, New Zealand.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society

|March 2, 2016

Summary

A rare thirteen-and-a-half syndrome, a variant of eight-and-a-half syndrome, occurred in a patient with post-transplant lymphoproliferative disorder affecting cranial nerves.

Area of Science:

Neurology
Oncology

Background:

Post-transplant lymphoproliferative disorder (PTLD) can manifest with diverse neurological complications.
Eight-and-a-half syndrome is a rare neurological condition characterized by specific cranial nerve palsies.

Observation:

A 50-year-old male patient presented with symptoms indicative of eight-and-a-half syndrome.
The patient had a history of post-transplant lymphoproliferative disorder.
Associated ipsilateral trigeminal nerve palsy was noted.

Findings:

The case describes a unique presentation of thirteen-and-a-half syndrome.
This syndrome involved the combination of eight-and-a-half syndrome and trigeminal nerve palsy.
The underlying cause was identified as post-transplant lymphoproliferative disorder.

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Implications:

This case expands the known clinical spectrum of eight-and-a-half syndrome.
It highlights PTLD as a potential cause of complex cranial nerve palsies.
Understanding this expanded syndrome aids in diagnosing and managing rare neurological complications post-transplant.